The article is devoted to conceptual bases of restructuring of modern manufacture. The basic approaches to re-structuring are formulated, the typology of restructuring of the industry is developed. The sequence of actions on development of processes of restructuring of territorial economic systems is certain. The methodology of conversion of the enterprises of a defense industrial complex as directions of re-structuring of the industry is offered. Basic provisions of a technique of designing of administrative decisions on restructuring and conversion of the high technology manufactures are formulated.

The main problems and peculiarities of modern socio-economic development of Russia regions are analyzed. The structure of state’s, region's, company’s development strategic aims concordance is given. The strategies of structural reforms of regions’ economy and main orientation of regional economic policy are examined. Taking into consideration the conditions of Orlovskaya area, the analysis of regions’ economy modern condition, orientation of its structural reforms, approaches to carrying out the structural policy is conducted.

In this article discussed problems of coordination of regional politics. Researching models of development regional economy and presents conceptions investment-programming development of regions. Formulate basic strategically direction of regional policy to investment-innovation aspects.

In this article discussed conceptual problems realization of scientifically and technical policy in Russia. Author research of changing to Academy of Science and high school, also researching the problems of risk to investment of contract by industrial scientifically production. Formulate basic strategically direction of innovation policy, including regional policy to investment-innovation aspects in Russia.